Washingtone: The researchers of Columbia University Medical Centre have clarified three fundamental issues about Alzheimer’s by using the high-resolution functional magnetic resonance imaging (fMRI) in patients with Alzheimer’s disease. These three fundamental issues are: where it starts, why it starts there and how it spreads.
The director of Alzheimer’s Disease Research Centre Scott A. Small said, “It has been known for years that Alzheimer’s starts in a brain region known as the entorhinal cortex.”
He also said, “But this study is the first to show in living patients that it begins specifically in the lateral entorhinal cortex, or LEC.”
He added, “The LEC is considered to be a gateway to the hippocampus, which plays a key role in the consolidation of long-term memory, among other functions. If LEC is affected, other aspects of the hippocampus will also be affected.”
The finding could also improve the early detection of disease, when drugs may be most effective.
Bureau Report
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